Ka Calorimeter Titration Isothermal (ITC)

ʻO ka Isothermal Titration Calorimeter (ITC) kahi mea hana i hoʻohana ʻia no ke ana pololei ʻana i nā pilina molekala a me nā waiwai thermodynamic. Loaʻa iā ia ka ʻikepili thermodynamic ma o ka nānā ʻana i ka wela i hoʻokuʻu ʻia a i ʻole i omo ʻia i ka wā o nā hopena a i ʻole nā ​​​​hanana hoʻopaʻa ʻana ma lalo o nā kūlana isothermal. Hiki i ka ITC ke hāʻawi i nā hopena thermal manawa maoli o nā hopena, e hiki ai ke nānā i nā ʻano thermodynamic e like me nā kūpaʻa hoʻopaʻa, ka wela hopena, nā loli ikehu manuahi, nā loli enthalpy, a me nā loli entropy i ka hoʻopaʻa ʻana o ka molekala, nā pilina ligand-receptor, nā kaʻina hana hoʻoheheʻe, a me nā hopena kemika a olaola paha. Hoʻohana nui ʻia ʻo ITC i ka biochemistry, ka hoʻomohala lāʻau lapaʻau, ka biology molekala, a me ka ʻepekema mea, e hōʻike ana i ka pololei a me ka ʻike kiʻekiʻe loa, ʻoi aku hoʻi i ke aʻo ʻana i nā pilina ma waena o nā protein a me nā ligands, nā waikawa nucleic a me nā molekala liʻiliʻi.